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Assays, reagents, kits, and other assorted products used to detect cellular apoptosis, determine the activity levels of caspase or cathepsin, or identify similar cellular activity.
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A remarkable feature of apoptosis is the degradation of chromosome DNA, which is a common phenomenon. The degradation is very specific and regular. DNA fragments break into different lengths are of 180 bp-200 bp, showing a specific ladder like ladder pattern in agarose gel electrophoresis. The kit uses TUNEL method and uses Terminal Deoxynucleotidyl Transferase(TdT) catalyzes the incorporation of CoraLite594-dUTP into the 3´-OH terminal of the broken DNA of apoptotic cells. DNA labeled with CoraLite594- dUTP can be observed directly by fluorescence microscope or quantified by flow cytometry. TUNEL can selectively detect apoptotic cells rather than necrotic cells or cells with DNA strand breaks caused by irradiation and drug therapy.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
The KILR Daudi (Human) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct death mediated by immuno-oncology treatments via ADCC, CDC, and ADCP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
The KILR BT-474 (Human) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct death mediated by immuno-oncology treatments via ADCC, CDC, and ADCP. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
The KILR DU-145 (Human) Stable Cell Pool Cytotoxicity Assay utilizes the engineered stable target cell pool that is used to measure direct cell death via ADCC, CDC, and ADCP. This complete kit includes cell pool vials and all required reagents for cell culture, maintenance, and running the assay.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More